Drostanolone, or drospanitol masteron, sold legally under the name Dromostol, Drolbin, and Masteron amongst others, is a non-steroidal anti-androgen that has been used in the treatment of breast cancer in both women and men but is no longer commercially available. It is usually given orally into the muscle. It causes a rapid increase in the rate of protein synthesis (phytoestrogen) and inhibits the enzyme associated with the breakdown of estrogen. This leads to the blocking of estrogen receptors and the subsequent blocking of anabolic steroids and the formation of androgenic byproducts such as testosterone and cortisol. A related hormone, the aromatase enzyme, is unaffected by the presence of the estrogens.
The blocking of these hormones results in the feminization of men, although this phenomenon is most pronounced in young teenage boys who have had their testicular glands removed (like those in men with a castrated reproductive organ) and adolescents who use significant amounts of anabolic steroids. Testosterone concentrations in body fluids are increased during and after anabolic steroid use, resulting in the presence of large amounts of free testosterone. These changes in sexual development may account for the accounts written by some authors referring to a feminization of men (Doleman & Masters, 1977; citing studies based on postmenopausal women). But these accounts are disputed by other authors, who point out that there is no evidence that estrogen levels in human breast tissue can change following the administration of anabolic steroids, and that the presence of free testosterone does not account for the development of femininity.
The mechanism whereby the estrogen-like effects occur in the body is not known. One possibility is that the production of progesterone (the female hormone) by the ovaries is stimulated by the anabolic effect of the anabolic (testosterone) – androgen compound, masteron. Another possibility is that, unlike the anabolic effects of masteron, the binding of the aromatase enzyme to the aromatocyanin receptor (the enzyme that senses porphyrins, a natural estradiol derivative of masteron) results in a concentration of free testosterone that is below the critical level that stimulates estrogen production.
Taking care to use diet supplements that contain substances like tongkat ali, tribulus terrestris, ashwagandha, muira puama or yohimbe can be effective in counterbalancing the production of anabolic hormones. Also available are substances like cortisol, thyroxine, magnesium, guggulipid, bromelain, melatonin, guarana, ginseng, damiana, valerian, thistle and green tea that exert estrogenic effects when used topically (not orally). In addition, you might consider adding some vitamin D to your regular vitamin intake. The American Society for Clinical Research reported in its recent review of herbal treatment for menopause that many herbs “with traditional Asian medicine” had “effective and notable antifungal properties.” Most of these herbs, the research found, are currently approved for use in the United States.
Using masteron to reduce breast cancer risk is still being studied, but there are encouraging indications from some sources. The National Institutes of Health recently announced that it plans to begin a clinical trial of the effect of masteron on breast cancer cells. At present, there’s no single oral prescription recommended for use in the treatment of breast cancer. But there are several oral and vaginal antifungal medications that have been approved by the FDA for the treatment of breast cancer and other tumors. These medications include the antineoplastic agents gemcitabine (ddI, Videx), zapycet, terbinafine, imidazolidine, cisplatin, paclitaxel, vincristine, nisindavan, trifluoperazine, ketoconazole and miscellaneous drugs like carbamazepine, leupeptin, methotrexate and carboplatinum.
According to reports, the most common side effects of taking in antineoplastic agents or anabolic steroids are vomiting, stomach pain, headaches, dizziness, diarrhea, changes in body color and changes in skin pigmentation, increased risk of infection and bleeding, stroke and liver malfunction. However, these side effects can subside if the dosage is reduced or the drug is discontinued. So using masteron to treat hair loss can be a promising treatment for people who are concerned about their health. However, masteron should only be prescribed to people with very good health who do not use other drugs such as anabolic steroids and corticosteroids.